The Intercellular Synchronization of Ca2+ Oscillations Evaluates Cx36-Dependent Coupling
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منابع مشابه
The Intercellular Synchronization of Ca2+ Oscillations Evaluates Cx36-Dependent Coupling
Connexin36 (Cx36) plays an important role in insulin secretion by controlling the intercellular synchronization of Ca(2+) transients induced during stimulation. The lack of drugs acting on Cx36 channels is a major limitation in further unraveling the molecular mechanism underlying this effect. To screen for such drugs, we have developed an assay allowing for a semi-automatic, fluorimetric quant...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0041535